G4416

Sigma

 

Anti-GABAA Receptor (α1 subunit) antibody produced in rabbit

affinity isolated antibody

MDL number:MFCD01092338

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Description

Immunogenpeptide corresponding to amino acids 28-43 of rat GABA(A) receptor α1 subunit.
Preparation NoteReconstitute the 0.05 mL vial with 50 μL deionized water. Reconstitute the 0.2 mL vial with 0.2 mL deionized water. After reconstitution, the antibody concentration is ~0.8 mg/mL.
Physical formLyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin, and 0.05% sodium azide.

Properties

antibody formaffinity isolated antibody
clone(polyclonal)
formlyophilized powder
mol wtantigen mol wt ~50 kDa
species reactivityrat, mouse, human (predicted), bovine (predicted), chicken (predicted)
availabilitynot available in Canada (due to temporary import restrictions; for questions or status updates, please email us at antibody.canada@sial.com)
application(s)immunoblotting: 1:400-1:1,000 using rat brain membranes
 immunohistochemistry: suitable using rat brain sections
Gene Informationhuman ... GABRA1(2554)
 rat ... Gabra1(29705)
 mouse ... Gabra1(14394)
storage temp.−20°C

Safety

WGK Germany2

References

referenceGao, B., et al., Neuron-specific expression of GABAA-receptor subtypes: differential association of the alpha 1- and alpha 3-subunits with serotonergic and GABAergic neurons. Neuroscience 54, 881-892, (1993) Abstract
 Gorman, D., et al., Early evidence of a regulated response to hypoxaemia in sheep that preserves the brain cortex. Neurosci. Lett. 394, 174-178, (2006) Abstract